An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16077 entries, 14165 authors and 1948 subjects. Updated: October 12, 2025

NYHAN, William Leo

1 entries
  • 14197

A familial disorder of uric acid metabolism and central nervous system dysfunction.

Amer. J. Med., 36, 561-570, 1964.

Lesch-Nyhan syndrome, a rare inherited disorder that affects about 1 in 380,000 live births. In their summary the authors described this as a new "syndrome consisting of hyperuricemia, mental retardation, choreoathetosis, and self-destructive biting." 

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: ENDOCRINOLOGY, PEDIATRICS