An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15961 entries, 13944 authors and 1935 subjects. Updated: March 22, 2024

CAVAZZANA, Marina

1 entries
  • 13943

Gene therapy of severe combined immunodeficiency (SCID)-XI disease.

Science, 288, 669-672, 2000.

In 1999, With Marina Cavazzana-Calvo and Salima Hacein-Bey, Fischer achieved the first clinical successes in the world of gene therapies for about ten bubble children,[8] two of whom unfortunately developed leukaemias after a few months, one of whom had died. The test was stopped urgently in 2002. The trial was restarted in 2004, according to a modified protocol using better retroviral vectors, and was stopped again in 2005 due to new complications. 



Subjects: GENETICS / HEREDITY › Gene Therapy / Human Gene Transfer